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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
21/01/2009 |
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Data da última atualização: |
06/05/2024 |
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Tipo da produção científica: |
Artigo em Anais de Congresso / Nota Técnica |
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Autoria: |
ARBEX, W.; SILVA, M. V. G. B.; COSTA, V. S.; CARVALHO, L. A. V. |
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Afiliação: |
Wagner Arbex, Embrapa Gado de Leite; Marcos Vinicius Gualberto Barbosa da Silva, Embrapa Gado de Leite; Vítor Santos Costa Universidade do Porto Portugal; Luís Alfredo Vidal de Carvalho, UFRJ. |
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Título: |
Prospecção automática de SNPs. |
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Ano de publicação: |
2008 |
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Fonte/Imprenta: |
In: CONGRESSO BRASILEIRO DE AUTOMÃTICA, 17., 2008, Juiz de Fora. Anais... Juiz de Fora: UFJF, 2008. 1 CD. |
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Idioma: |
Português |
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Palavras-Chave: |
Busca automatizada de polimorfismos de base única; Pipeline para identificação de polimorfismos de base única; Polimorfismo de base única. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/595914/1/ProspecAAo-automAtica-de-SNPs.pdf
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Marc: |
LEADER 00646nam a2200169 a 4500
001 1595914
005 2024-05-06
008 2008 bl uuuu u00u1 u #d
100 1 $aARBEX, W.
245 $aProspecção automática de SNPs.$h[electronic resource]
260 $aIn: CONGRESSO BRASILEIRO DE AUTOMÃTICA, 17., 2008, Juiz de Fora. Anais... Juiz de Fora: UFJF, 2008. 1 CD.$c2008
653 $aBusca automatizada de polimorfismos de base única
653 $aPipeline para identificação de polimorfismos de base única
653 $aPolimorfismo de base única
700 1 $aSILVA, M. V. G. B.
700 1 $aCOSTA, V. S.
700 1 $aCARVALHO, L. A. V.
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
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Biblioteca |
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Tipo/Formato |
Classificação |
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Registro |
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Registro Completo
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Gado de Leite; Embrapa Pecuária Sudeste. |
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Data corrente: |
17/12/2014 |
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Data da última atualização: |
05/02/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
MOKRY, F. B.; BUZANSKAS, M. E.; MUDADU, M. de A.; GROSSI, D. do A.; HIGA, R. H.; VENTURA, R. V.; LIMA, A. O. de; SARGOLZAEI, M.; MEIRELLES, S. L. C.; SCHENKEL, F. S.; SILVA, M. V. G. B.; NICIURA, S. C. M.; ALENCAR, M. M. de; MINARI, D. P.; REGITANO, L. C. de A. |
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Afiliação: |
MARCOS VINICIUS GUALBERTO B SILVA, CNPGL. |
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Título: |
Linkage disequilibrium and haplotype block structure in a composite beef cattle breed. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
BMC Genomics, London v. 15, S6, p. 1-9, 2014. |
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DOI: |
10.1186/1471-2164-15-S7-S6 |
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Idioma: |
Inglês |
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Notas: |
Suppl 7. |
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Conteúdo: |
Abstract. Background: The development of linkage disequilibrium (LD) maps and the characterization of haplotype block structure at the population level are useful parameters for guiding genome wide association (GWA) studies, and for understanding the nature of non-linear association between phenotypes and genes. The elucidation of haplotype block structure can reduce the information of several single nucleotide polymorphisms (SNP) into the information of a haplotype block, reducing the number of SNPs in a coherent way for consideration in GWA and genomic selection studies. Results: The maximum average LD, measured by r2 varied between 0.33 to 0.40 at a distance of < 2.5 kb, and the minimum average values of r2 varied between 0.05 to 0.07 at distances ranging from 400 to 500 kb, clearly showing that the average r2 reduced with the increase in SNP pair distances. The persistence of LD phase showed higher values at shorter genomic distances, decreasing with the increase in physical distance, varying from 0.96 at a distance of < 2.5 kb to 0.66 at a distance from 400 to 500 kb. A total of 78% of all SNPs were clustered into haplotype blocks, covering 1,57 Mb of the total autosomal genome size. Conclusions: This study presented the first high density linkage disequilibrium map and haplotype block structure for a composite beef cattle population, and indicates that the high density SNP panel over 700 k can be used for genomic selection implementation and GWA studies for Canchim beef cattle. MenosAbstract. Background: The development of linkage disequilibrium (LD) maps and the characterization of haplotype block structure at the population level are useful parameters for guiding genome wide association (GWA) studies, and for understanding the nature of non-linear association between phenotypes and genes. The elucidation of haplotype block structure can reduce the information of several single nucleotide polymorphisms (SNP) into the information of a haplotype block, reducing the number of SNPs in a coherent way for consideration in GWA and genomic selection studies. Results: The maximum average LD, measured by r2 varied between 0.33 to 0.40 at a distance of < 2.5 kb, and the minimum average values of r2 varied between 0.05 to 0.07 at distances ranging from 400 to 500 kb, clearly showing that the average r2 reduced with the increase in SNP pair distances. The persistence of LD phase showed higher values at shorter genomic distances, decreasing with the increase in physical distance, varying from 0.96 at a distance of < 2.5 kb to 0.66 at a distance from 400 to 500 kb. A total of 78% of all SNPs were clustered into haplotype blocks, covering 1,57 Mb of the total autosomal genome size. Conclusions: This study presented the first high density linkage disequilibrium map and haplotype block structure for a composite beef cattle population, and indicates that the high density SNP panel over 700 k can be used for genomic selection implementation and GWA studies for Canchim bee... Mostrar Tudo |
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Palavras-Chave: |
Composite; Desequilíbrio de ligação; Genome wide association studies; Halplotype block; Linjage disequilibirium; Polimorfismo de nucleotídeo único. |
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Thesagro: |
Gado de corte. |
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Thesaurus NAL: |
Beef cattle; Linkage disequilibrium; Single nucleotide polymorphism. |
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Categoria do assunto: |
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/119863/1/MOKRY.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/114007/1/PROCI-2104.00140.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/114252/1/1471-2164-15-S7-S6.pdf
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Marc: |
LEADER 02809naa a2200433 a 4500
001 2006604
005 2024-02-05
008 2014 bl uuuu u00u1 u #d
024 7 $a10.1186/1471-2164-15-S7-S6$2DOI
100 1 $aMOKRY, F. B.
245 $aLinkage disequilibrium and haplotype block structure in a composite beef cattle breed.$h[electronic resource]
260 $c2014
500 $aSuppl 7.
520 $aAbstract. Background: The development of linkage disequilibrium (LD) maps and the characterization of haplotype block structure at the population level are useful parameters for guiding genome wide association (GWA) studies, and for understanding the nature of non-linear association between phenotypes and genes. The elucidation of haplotype block structure can reduce the information of several single nucleotide polymorphisms (SNP) into the information of a haplotype block, reducing the number of SNPs in a coherent way for consideration in GWA and genomic selection studies. Results: The maximum average LD, measured by r2 varied between 0.33 to 0.40 at a distance of < 2.5 kb, and the minimum average values of r2 varied between 0.05 to 0.07 at distances ranging from 400 to 500 kb, clearly showing that the average r2 reduced with the increase in SNP pair distances. The persistence of LD phase showed higher values at shorter genomic distances, decreasing with the increase in physical distance, varying from 0.96 at a distance of < 2.5 kb to 0.66 at a distance from 400 to 500 kb. A total of 78% of all SNPs were clustered into haplotype blocks, covering 1,57 Mb of the total autosomal genome size. Conclusions: This study presented the first high density linkage disequilibrium map and haplotype block structure for a composite beef cattle population, and indicates that the high density SNP panel over 700 k can be used for genomic selection implementation and GWA studies for Canchim beef cattle.
650 $aBeef cattle
650 $aLinkage disequilibrium
650 $aSingle nucleotide polymorphism
650 $aGado de corte
653 $aComposite
653 $aDesequilíbrio de ligação
653 $aGenome wide association studies
653 $aHalplotype block
653 $aLinjage disequilibirium
653 $aPolimorfismo de nucleotídeo único
700 1 $aBUZANSKAS, M. E.
700 1 $aMUDADU, M. de A.
700 1 $aGROSSI, D. do A.
700 1 $aHIGA, R. H.
700 1 $aVENTURA, R. V.
700 1 $aLIMA, A. O. de
700 1 $aSARGOLZAEI, M.
700 1 $aMEIRELLES, S. L. C.
700 1 $aSCHENKEL, F. S.
700 1 $aSILVA, M. V. G. B.
700 1 $aNICIURA, S. C. M.
700 1 $aALENCAR, M. M. de
700 1 $aMINARI, D. P.
700 1 $aREGITANO, L. C. de A.
773 $tBMC Genomics, London$gv. 15, S6, p. 1-9, 2014.
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